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Upneeq

What is Upneeq?

Upneeq is the only FDA-approved prescription eyedrop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes. If your eyes look “tired” or “sleepy,” you may have a condition called acquired blepharoptosis (also known as acquired ptosis or low-lying lids).

Why do my eyelids look low?

If your eyes look “tired” or “sleepy,” you may have a condition called acquired blepharoptosis (also known as acquired ptosis or low-lying lids).

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How does Upneeq work?

Upneeq (oxymetazoline hydrochloride ophthalmic solution), 0.1% is an eye drop that should be inserted once a day, one drop per eye. (Each single-use vial of Upneeq contains enough solution to treat one or both eyes at a time.) Upneeq contains oxymetazoline, an alpha-adrenergic agonist that triggers the levator palpebrae muscle (Muller’s or Mueller’s muscle), causing the muscle to contract and raise the upper eyelid.

 

Upneeq works by stimulating an involuntary eyelid muscle, the Muller’s muscle, to contract.

 

In clinical studies, the average amount of upper eyelid lift was 1 mm. While this minor lift will not give you the dramatic results possible with surgery, this small lift can be cosmetically and/or medically beneficial to many patients.

How long Upneeq last?

Each dose (one drop daily) of Upneeq was shown to be effective for at least 6 hours in clinical studies.

Is Upneeq FDA-approved to be safe and effective?

Upneeq is FDA-approved to be both safe and effective for the treatment of acquired eyelid ptosis in adults. To gain FDA approval, Upneeq showed effectiveness in two 6-week trials that followed 304 patients with acquired blepharoptosis. A third study was also conducted to establish that the eye drop is safe.

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